Dr. Kristian M. Hargadon ’01 Publishes Article on Tumor-altered Dendritic Cells

Elliott Assistant Professor of Biology Dr. Kristian M. Hargadon ’01 recently published an article on tumor-altered dendritic cells in Frontiers in Immunology, the official journal of the International Union for Immunological Societies.  Frontiers Journals have recently partnered with Nature Publishing Group (NPG), publisher of the Nature journal series, which has over 150 years experience as the leading publisher of groundbreaking science.  Together, Frontiers and NPG are working to empower researchers to change the way science is communicated, through open access publication and open science tools.  Dr. Hargadon’s article in Frontiers in Immunology highlights recent advances in the field of tumor immunology as they relate to our understanding of how tumors alter the function of dendritic cells, an immune cell type critical for the induction of anti-tumor immune responses.  The article discusses not only how tumors alter dendritic cell function but also how these tumor-altered dendritic cells impact the quality of overall anti-tumor immunity.  It also emphasizes recent work that has aimed to enhance dendritic cell-mediated anti-tumor immune responses through cancer immunotherapy strategies.  Lastly, the article highlights questions in the field that remain to be answered as well as strategies for addressing these problems that may aid in the development of novel and improved anti-cancer treatment regimens.  Dr. Hargadon’s article is the first published in what will be a series of articles from investigators all over the world in a Special Issue of this journal focusing on Tumor/Dendritic Cell Interactions.