Christopher M. Ferrante ’15


Dane R.C. Asuigui ’16
Travis B. Goodloe ’16
Brian N. Hulsizer ’16
Linh V. Nguyen ’16
Daniel Osarfo-Akoto ’15
Shaquann S. Seadrow ’16


Michael J. Wolyniak
Department of Biology

Cover Photo: Green fluorescent protein (GFP) has revolutionized molecular biology by allowing scientists to label individual proteins in a cell or, as in this photo, entire organisms.  Here, the nematode Caenorhabditis elegans, a common model organism in the study of developmental biology and genetics, is labeled with GFP to provide a clear view of its body plan.  The photograph was taken in the Fall 2014 semester in Gilmer Hall at Hampden-Sydney.  Note the unborn C. elegans that can be seen developing inside the adult nematodes.  (From Grayland W. Godfrey ’15)


News from the Hampden-Sydney Science Departments


The Energy Research Laboratory at Hampden-Sydney College
Professor Paul F. Hemler, Department of Mathematics and Computer Science

Solar thermal panel closed loop system design: Construction and application
Caleb M. Bowyer ’16

A comparison of curing rates for insulated and non-insulated concrete
Travis M. Newcomb ’18

Arduino temperature-monitoring systems for the Hampden-Sydney College Energy Research Lab
B. Branch E. Vincent ’16 and Zachary R. Carter ’17


Synthesis and characterization of some novel tetradentate Schiff base ligands and their metal(II) complexes
Dane R.C. Asuigui ’16

ESR studies of free radical intermediates in the chemical oxidation of phenols and other compounds by cerium (IV)
Brant D. Boucher ’17

Effects of chemical pollutants and an emerging infectious disease on juvenile red-eared slider turtles (Trachemys scripta elegans)
E. Davis Carter ’15

Synthesis, metal-coordination, and characterization of existing and novel Schiff base ligands
William R. Echols ’17

The effect of timing of the cognitive and standard interviews on memory retrieval of a previously witnessed event
Scott M. Foster ’17

The Prescription Problem: The impact of prescription drugs for anxiety and depression on adolescent brain maturation
Aaron S. Gilani ’15

Behavioral characterization of a daf-18 mutation in Caenorhabditis elegans
Grayland W. Godfrey ’15

How well does an aggressive invasive plant species, Centaurea stoebe ssp. Micranthos (Asteraceae), perform when placed in different substrates?
Erik W. Kellogg ’15

A continued study of the invasive potential and competitiveness of the invasive plant Centaurea stoebe as compared to the native plant Lespedeza capitata
Sean G. Kellogg ’15

A study of survey sampling variable selection techniques in a simulation setting
Zachary A. King ’15

Testing of multiple methods for the synthesis of tetradentate Schiff base ligands and their characterization and metal coordination
Benjamin W. Lam ’17

Analysis and comparison of diesel fuel for organic and metal content via MP-AES and GC-MS
James H. Lau ’17

Treatment of lactose intolerance via β-galactosidase overexpression in supplemental microflora
Christian R. Lehman ’14

Determining the kinetic coefficient of ice using a tribometer
J. Robert McGhee III ’15

Synthesis of a family of chiral asymmetric Schiff base ligands
Shawn M. Stum ’15

ESR studies of free radical intermediates in the chemical oxidation of syringaldazine and related compounds by cerium (IV)
Jefferson C. Thompson ’16

Mutational analysis of TEP1, a budding yeast homologue of the human prostate cancer factor PTEN
Stephen L. Woodall ’15




John R. Dekarske ‘14


Christopher M. Ferrante ‘15
Alan J. Fish ‘14
William D. Hudson ‘14
Shaquann S. Seadrow ‘16


Michael J. Wolyniak
Department of Biology

Cover Photo: The Phamerator database is used to compare whole bacteriophage genomes for similarities and differences that will uncover information on the progression of bacteriophage evolution.  The coloration between the lines in the above figure indicate regions of high sequence similarity between the genomes under comparison.  (From James B. Hughes ’14)


News from the Hampden-Sydney Science Departments


Genetically Based: The Search for the Gay Gene
Christopher M. Ferrante ’15

The wrong question about the “wrong” group: considering the topic of homosexuality from a humanities perspective
William D. Hudson ’14


Synthesis and Characterization of Organometallic Catalyst Complexes and Their Ligand Subcomponents
R. Lee Ayscue ’15

Examining Head Injury: The Efficiency and Longevity of a Modern Lacrosse Helmet
W. Burke Best ’13

Interactions between High Mobility Group Box 1 (HMGB1) Protein and Toll-Like Receptor 4 (TLR4) And Their Roles in Inflammation Responses in the Brain and Liver: A Scientific Review
J. Drake Bishop ’14

The Effects of Ibotenic Acid Lesions to Auditory and Visual Sectors of the Thalamic Reticular Nucleus During a Visual Discrimination Task with an Auditory Distraction
Cody N. Castelvecchi ’13

A Simple Planetary Evolution Model Using the Solar Nebular Theory
Jamshaid R. Chaudhry ’16

Development of LabVIEW Software with NIEHS DOS-based Software Program Electron Spin Resonance (ESR) Capabilities for Post-processing ESR Spectra
Meade C. Edmunds ’14

Fluorescent Spectroscopic Comparison of Phenotypes of Different Strains of Saccharomyces cerevisiae with Point Mutations of the BRR6 Gene
Alan J. Fish ’14

‘Broinformatics: The Study and Analysis of Cluster K Mycobacteriophage Genomic Data
James B. Hughes ’14

How well does an aggressive invasive plant species, Centaurea stoebe (Asteraceae), perform when placed in different substrates?
Erik W. Kellogg ’15

Anomalous Acoustics in Crawley Forum: An Introductory Acoustical Analysis of Crawley Forum
Carson T. Maki ’15

The Scientific Instrument: The Case for Constructive Empiricism over Scientific Realism
Dylan S. Schlaak ’14




Yonathan T. Ararso ’13
John H. Bishop, Jr. ’13
Ke Shang ’13


W. Burke Best ‘13
John R. Dekarske ‘14
Alan J. Fish ‘14
William D. Hudson ‘14
David C. Williams ‘14


Michael J. Wolyniak
Department of Biology

Cover Photo: This figure shows the block diagram of a virtual instrument (VI) designed to operate a UV-vis spectrometer and a potentiostat in tandem. This particular VI aids the operator in conducting spectroelectrochemistry experiments, and it will also automatically save the results of the experiments to text files for data analysis (From Stephen D. Nelson ‘13).


News from the Hampden-Sydney Science Departments

Letter to the Editors


Playing God: The Ethics of Euthanasia
Christopher M. Ferrante ’15

The science and philosophy of Cherokee Indian medicine: A natural alternative to Western solutions
S. Barron Frazier ’12

Calling all whistleblowers: Research fraud and the stopgap solution
Stewart J. Neifert ’12

Complexities of doctor/patient relationships
T. Samuel Robinson ’15

Ethical analysis of placebo testing: Clinical trials vs. clinical treatments
Parker C. Vukich ’15


A study of the genetics of Arabidopsis thaliana and Saccharomyces cerevisiae
J. Drake Bishop ’14

Electron spin resonance and cell biology studies of potentially hepatotoxic kava root extracts
Ian Giles ’12

Realism in Messiaen’s Oiseaux Exotiques: A Correlation
Janahgir Iqbal ’15

Reflection of personality through a Facebook analysis
Kevin W. Laffond ’12

Construction and testing of LabVIEW software to interface with a Princeton applied research model 273 potentiostat and an HP Model 8452A photospectrometer
Stephen D. Nelson ’13

Modeling white dwarf star magnetization
Edward K. Park ’15

The effects of environmental stressors and the pathogen ranavirus on survival and health of juvenile freshwater turtles
Francis J. Polakiewicz ’14

BIS/BAS and college alcohol use: motivation, consequences, and attention
Frank R. Rose ’12

Formulation of transparent melt and pour soaps without petroleum derivatives
R. Kent F. Saxton ’13 and Brandon J. Crosby ’13

Synthesis and characterization of a bifunctional porphyrin: Electrochemical modulation of oxygen binding
Richard A. Whitt ’12

Inheritance patterns in monohybrid and dihybrid crosses for sepia eye color and apterous (wingless) mutations in Drosophila melanogaster
Spencer T. Wiles ’14



Science Journal 2012 banner


Yonathan T. Ararso ’13
John H. Bishop, Jr. ’13
Osric A. Forrest ’12
Ke Shang ’13


Michael J. Wolyniak
Department of Biology

Cover Photo: Using immunofluorescence and Calcofluor White staining, proteins called septins can be observed at the division points of budding yeast cells (Saccharomyces cerevisiae) along with an outline of the cell wall. From Nathaniel Thomas ’11 (see below). Photo credit: Jonathan Park ’12


Isolation, purification, and characterization of mycobacteriophage HerbSipe
Ian C. Giles ’12

The effects of transcranial direct current stimulation and an enriched environment on working memory in the rat model
Andrew W. Nance ’12

The rostral thalamic reticular nucleus: How lessons to the rostral TRN effect performance in rate on a visual discrimination task
Stewart J. Neifert ’12

The C-terminal region of Apq12 is potentially involved in the regulation of cell cycle progression and cell separation
James R. Oliver ’11

Musical rendering of mathematical objects
Erik A. Schafer ’13

Mathematical synthesis and analysis of sound
Ke Shang ’13

The role of yeast nuclear membrane proteins Brr6 and Brl1 in cell wall integrity and cell separation
Nathaniel J. Thomas ’11

Possible arabinogalactan stabilization of unstable phenoxy radicals produced by horseradish peroxidase
Nathaniel J. Thomas ’11

Synthesis and ESR and ENDOR investigation of phenalenyl radical, a useful ENDOR reference compound
Arne Ulbrich ’11